1.Title：Studies of the polymorphism of sodium valproate. (Ger.). Authors：Kleinebudde P; Thies R Publication Name：Sci.Pharm. Publication Year：1999 Keywords：Valproate Sodium/Oc Crystal/Ft Polymorphism/Ft Calorimetry/Ft X-Ray- Diffraction/Ft Analysis/Ft Crystallography/Ft Anticonvulsants/Ft Antimanics / Ft Oc / Ft Extract：2 Crystal modifications (M1 and M2) of Na valproate (NV) have been detected at RT, while a further form (M3) occurred at temperatures above 100 deg. Untreated NV, which had been recrystallized from toluene or ethyl acetate occurred as modification M1. These modifications were examined by thermoanalytical (DSC, thermogravimetry) and X-ray crystallographic methods. 2.【題名】Polymorphism of sodium valproate 【作 者】Mifsud, H.;Miguel, L.;Lavastre, V.;Maire, G. 【刊 名】Calorim. Anal. Therm. Calorimetrie et Analyse Thermique 【出版日期】1993 【卷 號(hào)】Vol.24 【頁 碼】309-312 【關(guān)鍵詞】polymorphism sodium valproate Polymorphism of sodium valproate 1069-66-5 polymorphism 【摘 要】Polymorphism anal. is of fundamental pharmaceutical importance for correct development of a drug, as it provides valuable knowledge of its biopharmaceutical and technol. aspects. Indeed, different polymorphs exhibit different phys. properties that can affect bioavailability. Polymorphism screening has been developed in the authors' lab., based on crystn. parameter variations for a given drug in soln. Sodium valproate is an anti-epileptic drug commercialized under the name Depakine. Five polymorphic forms were obtained by the screening and characterized by differential scanning calorimetry, X-ray powder diffractometry, thermogravimetry and IR spectroscopy. The relationships between these forms were examd.   [更多]

求購左氧氟沙星片標(biāo)準(zhǔn)   [更多]

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詳細(xì)情況 藥品：獸用biocid-30（商品名）消毒劑； 檢索途徑：美國或者日本獸藥審批網(wǎng)站（可以查到獸用消毒劑產(chǎn)品信息）； 具體要求：請(qǐng)寫明具體網(wǎng)址，能夠查詢到該產(chǎn)品的信息，便交易成功； 交稿方式：直接點(diǎn)擊交稿在線交稿就是了，我會(huì)每天過來看的，謝謝各位藥智的戰(zhàn)友們； 提醒：在FDA動(dòng)物藥品中，可以查詢到一般動(dòng)物藥，但是查不到獸用消毒劑。   [更多]

購買 藥物警戒系統(tǒng)主文件+藥物警戒計(jì)劃 模板   [更多]

天晴，潤(rùn)眾制藥甲磺酸伊馬替尼原料藥標(biāo)準(zhǔn)！   [更多]

Journal of General Chemistry, 1993, vol. 63, # 3.2, p. 424 - 427   [更多]

求聚多卡醇注射液最新質(zhì)量信息   [更多]